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Published Research

Roche NimbleGen array technology has helped power the research behind 100+ peer-reviewed publications. Search our publication list to learn more about our technology and the science it supports.

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Rfx6 directs islet formation and insulin production in mice and humans.

Smith S
, Qu H, Taleb N, Kishimoto N, Scheel D, Lu Y, Patch A, Grabs R, Wang J, Lynn F, Miyatsuka T, Mitchell J, Seerke R, Desir J, Eijnden SV, Abramowicz M, Kacet N, Weill J, Renard M, Gentile M, Hansen I, Dewar K, Hattersley A, Wang R, Wilson M, Johnson J, Polychronakos C, and German M.
Nature
 463 (7282), 775-780.
11 Feb 2010
Sequence Capture

A comprehensive resequence analysis of the KLK15-KLK3-KLK2 locus on chromosome 19q13.33.

Parikh H
, Deng Z, Yeager M, Boland J, Matthews C, Jia J, Collins I, White A, Burdett L, Hutchinson A, Qi L, Bacior JA, Lonsberry V, Rodesch MJ, Jeddeloh JA, Albert TJ, Halvensleben HA, Harkins TT, Ahn J, Berndt SI, Chatterjee N, Hoover R, Thomas G, Hunter DJ, Hayes RB, Chanock SJ, and Amundadottir L.
Human genetics
 127 (1), 91-99.
Jan 2010
Sequence Capture

Genome-wide analysis of allelic expression imbalance in human primary cells by high-throughput transcriptome resequencing.

Heap GA
, Yang JHM, Downes K, Healy BC, Hunt KA, Bockett N, Franke L, Dubois PC, Mein CA, Dobson RJ, Albert TJ, Rodesch MJ, Clayton DG, Todd JA, van Heel DA, and Plagnol V.
Human molecular genetics
 19 (1), 122-134.
1 Jan 2010
Sequence Capture

Inferring tumor progression from genomic heterogeneity

Navin N
, Krasnitz A, Rodgers L, Cook K, Meth J, Kendall J, Riggs M, Eberling Y, Troge J, Grubor V, Levy D, Lundin P, Månér S, Zetterberg A, Hicks J, and Wigler M.
Genome Research
 20 (1), -.
1 Jan 2010
DNA sequence capture and enrichment by microarray followed by next-generation sequencing for targeted resequencing

Chou L
, Liu CJ, Boese B, Zhang X, and Mao R.
Clinical chemistry
 56 (1), 62-72.
Jan 2010
Sequence Capture

The Wnt receptor, Lrp5, is expressed by mouse mammary stem cells and is required to maintain the basal lineage.

Goel S

PloS one
 4 (8), e6594.
2009
Gene Expression

Exome sequencing of a multigenerational human pedigree.

Hedges D
, Burges D, Powell E, Almonte C, Huang J, Young S, Boese B, Schmidt M, Pericak-Vance MA, Martin E, Zhang X, Harkins TT, and Züchner S.
PloS one
 4 (12), e8232.
2009
Sequence Capture

Transformation of chronic lymphocytic leukemia/small lymphocytic lymphoma to interdigitating dendritic cell sarcoma

Fraser CR
, Wang W, Gomez M, Zhang T, Mathew S, Furman RR, Knowles DM, Orazi A, and Tam W.
American journal of clinical pathology
 132 (6), 928-939.
Dec 2009
CGH/CNV

Homozygous deletion of MTAP gene as a poor prognosticator in gastrointestinal stromal tumors.

Huang H
, Li S, Yu S, Chou F, Tzeng C, Hu T, Uen Y, Tian Y, Wang Y, Fang F, Huang W, Wei Y, Wu J, and Li C.
Clinical cancer research : an official journal of the American Association for Cancer Research
 15 (22), 6963-6972.
15 Nov 2009
CGH/CNV

Epigenetics of multiple myeloma after treatment with cytostatics and gamma radiation.

Krejcí J
, Harnicarová A, Streitová D, Hájek R, Pour L, Kozubek S, and Bártová E.
Leukemia research
 33 (11), 1490-1498.
Nov 2009
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