SeqCap EZ Designs
Capitalize on our expertise with SeqCap EZ Designs-custom target enrichment designs developed in collaboration with researchers like you. Built upon our empirically optimized probe design algorithm and high efficiency uniformity of capture, SeqCap EZ Designs offer maximum performance for focused capture pools. These designs have been through rigorous development by their designers, tested for accuracy, probe spacing and optimized for research. Apply our proven designs to your focused research. Order your SeqCap EZ Design today.
Comprehensive Cancer Design
 SeqCap EZ Design: Comprehensive Cancer Design |
 Organism: Human |
 Genome Build: HG19 |
 Design File: Comprehensive Cancer Design (362 KB .zip) |
 Collaborator: Roche NimbleGen |
|
 Specifications/Details: The Comprehensive Cancer Design is a 4Mb design and targets 578 cancer genes. The genes were gathered from the Sanger Institute Cancer Gene Census Database and the NCBI Gene Tests databases. |
|
 |
|
Ordering Information |
|
Neurology Panel Design
SeqCap EZ Design: Neurology Panel Design |
Organism: Human |
Genome Build: HG19 |
Design File: Neurology Panel Design (154 KB .zip) |
Collaborator: Roche NimbleGen |
|
Specifications/Details: The Neurology Panel Design is a 1.5Mb design and targets 256 genes associated with 87 neurological disorders. The genes were gathered from the National Institute of Neurological Disorders and Stroke and NCBI Gene Tests databases. |
|
Flyer: Neurology Panel Design Flyer |
|
Ordering Information |
|
50 Mb Human UTR Design
SeqCap EZ Design: 50 Mb Human UTR Design |
Organism: Human |
Genome Build: HG19 |
Design File: 50 Mb Human UTR Design (5.4Mb .zip) |
Collaborator: Roche NimbleGen |
|
Specifications/Details: UTRs are untranslated regions on the 5’ and 3’ side of genes. The 3’ UTR contains regulatory elements that are involved in the control of expression of many genes. This design is a 50Mb capture library targeting these regions. |
|
Flyer: SeqCap EZ Exome +UTR Flyer |
|
Ordering Information |
|
Soy Exome Design
SeqCap EZ Design: Soy Exome Design |
Organism: Soy |
Genome Build: Joint Genome Institute |
Design File: Soy Exome Design (85.3Mb .zip) |
Collaborator: Roche NimbleGen |
|
Specifications/Details: The Soy Exome is an 85.3Mb design that targets 95.3% of the bases associated to the exon of 46,367 soy genes. We recommend the use of SeqCap EZ Developer Reagent (Cat. No.06684335001) for effective enrichment of the soybean exome. |
|
Technical Note: Soybean Exome Capture-Technical Note |
|
Ordering Information |
|
Mouse Exome Design
SeqCap EZ Design: Mouse Exome Design |
Organism: Mouse |
Genome Build: C57BL/6J, NCBI37, MM9 |
Design File: Mouse Exome Design (10.2Mb .zip) |
Collaborator: Roche NimbleGen/Mouse Consortium |
|
Specifications/Details: The coding sequence selected for the mouse exome probe pool design includes 203,225 exonic regions, including microRNAs, and collectively comprises over 54.3 Mb of target sequence (C57BL/6J, NCBI37/mm9). The design was based on a unified, Mouse Genome Database-curated gene set, consisting of non-redundant gene predictions from the National Center for Biotechnology Information (NCBI), Ensembl and The Vertebrate Genome Annotation (VEGA) database. To manage the size of the probe pool and to avoid non-uniquely mappable regions, we excluded olfactory receptors and pseudogenes from the target sequence. In cases where an exon contained both UTR and coding sequence, the UTR sequence was included in the design. |
|
Publications: http://www.ncbi.nlm.nih.gov/pubmed/21917142 |
|
Ordering Information |
|
Human MHC Design
SeqCap EZ Design: Human MHC Design |
Organism: Human |
Genome Build: HG19 |
Design File: Human MHC Design (271Kb .zip) |
Collaborator: Roche NimbleGen/BGI |
|
Specifications/Details: Targets the MHC region (3.37Mb), 1.6Mb of regions surrounding the MHC, and 8 known haplotypes with a total design of 4.97Mb. |
|
Publications: http://www.roche.com/media/media_releases/med_dia_2011-11-28.htm |
|
Ordering Information |
|
Baylor VCRome Design
SeqCap EZ Design: Baylor VCRome Design |
Organism: Human |
Genome Build: HG18 |
Design File: Baylor VCRome Design (7.0Mb .zip) |
Collaborator: Baylor |
|
Specifications/Details: The Baylor VCRome is an Exome design form the Baylor College of Medicine. The VCR in VCRome stands for Vega, CCDS, and RefSeq databases. |
|
Publications: http://genomebiology.com/content/pdf/gb-2011-12-7-r68.pdf |
|
Ordering Information |
|
