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DNA Methylation - Product Info


Roche NimbleGen Systems provides the most sensitive and specific DNA methylation services on the market. The preferred use of MeDIP (methylated DNA immunoprecipitation)1,2,3 or the MIRA (MBD protein) method4,5, coupled with NimbleGen arrays, enable you to rapidly identify methylated regions within a target genome in a high-throughput manner. These arrays allow you to determine promoter and genic DNA methylation within the genome as well as compare differential methylation between cells, tissues, and tumor samples. NimbleGen’s DNA methylation services are becoming increasingly recognized as the platform of choice, with an expanding list of peer-reviewed publications.

  1. Weber M, et al. Chromosome-wide and promoter-specific analyses identify sites of differential DNA methylation in normal and transformed human cells.
  2. Weber M, et al. Distribution, silencing potential and evolutionary impact of promoter DNA methylation in the human genome.
  3. Zilberman D, et al. Genome-wide analysis of Arabidopsis thaliana DNA methylation uncovers an interdependence between methylation and transcription. [Watch the Zilberman webinar]
  4. Rauch T, et al. MIRA-Assisted Microarray Analysis, a New Technology for the Determination of DNA Methylation Patterns, Identifies Frequent Methylation of Homeodomain-Containing Genes in Lung Cancer Cells.
  5. Rauch T, et al. Homeobox gene methylation in lung cancer studied by genome-wide analysis with a microarray-based methylated CpG island recovery assay.
Advantages and Applications

High-Resolution, High-Throughput Analysis of DNA Methylation

NimbleGen’s current high-density microarrays contain 385,000 probes on a single glass slide, allowing for coverage of up to 40Mb of genomic DNA per array. NimbleGen’s arrays will eventually contain more than 2.1 million probes (HD2) by mid-2008; making high throughput of DNA methylation samples much more realistic. With our 385,000 probe density, the entire non-repetitive human and mouse genomes can be surveyed at 100bp intervals, each with a set of 38 arrays (10 arrays with the introduction of HD2 arrays).

High Sensitivity

In the MeDIP DNA methylation analysis method, genomic DNA samples are immunoprecipitated with an anti-5-methyl-cytidine antibody and compared to control input DNA. The two samples are differentially labeled and hybridized to a single array as a two-color experiment. The intensity ratio of immunoprecipitated to control DNA is plotted versus genomic position to identify regions where increased signal (i.e. DNA fragment enrichment) is observed relative to the control sample. NimbleGen's DNA methylation arrays can detect as low as two methylated CpGs in a 500bp DNA fragment.

Figure 1

Identification of DNA Methylation Using NimbleGen Arrays - From the raw data, NimbleGen generates scaled log2-ratio data for IP/input. A statistical method is used to generate p-value enrichment data for each probe; peaks (methylated regions) are then generated based on the p-value data. NimbleGen also provides gene annotations and CpG island annotations.

Applications

  • Unbiased identification of methylated regions in a high genomic coverage manner
  • Correlation of promoter and genic DNA methylation with gene expression
  • Comparison of DNA methylation patterns between cells, tissues, and tumor samples
Figure 2

Detection of Differential DNA Methylation - Human (hg17) ENCODE tiling arrays were used to detect DNA methylation using MeDIP from two different tumor samples. Tumor B samples contain more DNA methylation events in this region when compared to tumor A samples.

Array Designs

NimbleGen has a range of DNA methylation microarray designs to choose from, or you can customize the array probe set to your specifications. The existing designs include a whole genome survey sets, consisting of a uniform tiling arrays covering all unique regions of the human genome, and a CpG island plus promoter arrays format, containing all UCSC annotated CpG islands in addition to proximal promoter regions, and promoter array designs aimed at known promoter regions. For custom designs, researchers can specify their regions of interest for a fine-tiling or promoter specific design or design their own targeted probes for a tailored array solution.

  • Whole-Genome Survey Sets – These sets tile uniformly across all unique, repeat-masked regions of a genome at an average probe spacing of 100bp or less. Human, mouse, Arabidopsis, rat, dog, and chicken genomes are currently available; additional genome array designs will be added as they become available. Order the entire genome set or individual arrays.
  • Promoter Sets – NimbleGen offers three different types of promoter designs to suit your DNA Methylation analyses:
    1. RefSeq Promoters are single array designs containing all known well-characterized RefSeq genes. The promoter regions on this array are covered by 50-75mer probes with approximately 100bp spacing, dependent on the sequence composition of the region. Designs are available for human and mouse.
    2. Two-Array Sets contain all annotated splice variants and alternative transcription start sites. This array set provides the most comprehensive tool for genome-wide mapping of transcriptional regulatory elements including all RefSeq genes, the Mammalian Gene Collection, and UCSC known genes to encompass the most comprehensive list of transcripts available. Designs are available for human, mouse, rat and Arabidopsis thaliana
    3. RefSeq XM Promoters are single array designs containing model reference sequences produced by NCBI's Genome Annotation Project (those accessions beginning with XM) that are predicted by genome sequence analysis. The entries represent ab initio predictions, or have some level of transcript or homology to known genes to support the gene predictions. They represent the transcripts and proteins that are annotated on the NCBI Contigs and they may be different from GenBank submissions for mRNAs and/or the curated RefSeq records with NM,NR,NP accession prefixes. Designs are available for human and mouse.

    Promoter Set Region Stats

     Design TypeDesign NameRegionsAvg. Region SizeTotal CoverageTranscripts Represented
    A
    R
    A
    B
    I
    D
    O
    P
    S
    I
    S    		Minimal PromoterATH6 min promoter24173168141Mbp30516
    Two-Array SetATH6 promoter 1 of 26335633440Mbp15177
    Two-Array SetATH6 promoter 2 of 26442632141Mbp15392
    H
    U
    M
    A
    N    		RefSeq PromoterHG18 RefSeq promoter18028281951 Mbp24659
    Two-Array SetHG18 promoter 1 of 211417474554 Mbp29028
    Two-Array SetHG18 promoter 2 of 211630477056 Mbp30329
    RefSeq XM PromoterHG18 RefSeqXM promoter49101191759 Mbp8045
    M
    O
    U
    S
    E    		RefSeq PromoterMM8 RefSeq promoter17354258245 Mbp19489
    Two-Array SetMM8 promoter 1 of 210807442248 Mbp24096
    Two-Array SetMM8 promoter 2 of 210825441248 Mbp24209
    RefSeq XM PromoterMM8 RefSeqXM promoter5980949657 Mbp8136
    R
    A
    T    		RefSeq PromoterRN34 promoter15398287344Mbp21632
    Two-Array SetRN34 promoter 1 of 27877605048Mbp11280
    Two-Array SetRN34 promoter 2 of 28034607349Mbp11553


    To download a spreadsheet of all the genes whose promoters are tiled on NimbleGen promoter arrays, click here for HG18 or here for MM8. Genes represented on NimbleGen expression arrays are also listed for human (60mers, 8 probes/transcript) and mouse (60mers; 9 probes/transcript). The start column indicates the starting position of the transcript in the genome; if the transcript is on forward (+) strand, this is the putative transcription start site. The stop column indicates the ending position of the transcript in the genome; if the transcript is on reverse (-) strand, this is the putative transcription start site.
  • CpG Island-Plus-Promoter Arrays – A single array design covers all UCSC-annotated CpG islands and promoter regions for all RefSeq genes. The promoter region covered is 1kb for human and 1.8kb for mouse and rat (due to a reduced frequency of CpG islands in the mouse and rat genomes). Small CpG islands are extended at both ends for a total coverage of 700bp for more reliable detection. DNA methylation positive control regions, such as the HoxA gene cluster, H19/IGF2 cluster, KCNQ1 cluster, and IGF2R gene, are also included on the array.
  • Custom Tiling Arrays – For a completely tailored DNA methylation array, customer specified genomic regions of interest are tiled with the same stringent probe selection methodology as used in NimbleGen’s catalog designs at the desired tiling density. Please contact NimbleGen Sales for a quotation or contact NimbleGen Technical Service with any questions about DNA methylation custom tiling arrays.
Delivery and Service Options

DNA Methylation Array Delivery

Customers can purchase catalog arrays or custom arrays from NimbleGen, and perform the array experiments at their own laboratories or core facilities. NimbleGen arrays are synthesized on standard-sized glass microscope slides and are compatible with a range of hybridization, washing and scanning instrumentation. NimbleGen provides a complete user’s guide to support customers with sample processing, array hybridization, scanning, data extraction, and analysis. Please contact NimbleGen for a list of required equipment and reagents. NimbleGen provides NimbleScan™ and SignalMap™ software to DNA methylation array delivery customers, which enables the same data analysis and visualization to be performed as in the full service mode. NimbleGen also offers a training program to get you up and running with NimbleGen arrays quickly.

Array Specifications

Probe Lengths 50-75mer Probes
Total Features 385,000
Overall Slide Dimensions 1" x 3" (25 x 75mm)
Array Size 17.4mm x 13mm
Feature Size 16μm x 16μm

DNA Methylation Analysis Service

DNA methylation microarray service consists of the following steps:

  1. The customer selects a catalog DNA methylation array design or works with NimbleGen's Bioinformatics team to create a custom array design. NimbleGen manufactures the array.
  2. The customer prepares their samples, including immunoprecipitation with anti-5-methyl-cytidine (MeDIP, recommended) or the MBD protein method. The DNA is amplified (if required) according to recommended protocols and samples are shipped to NimbleGen's Service Lab.
  3. NimbleGen labels the samples, performs the hybridization, scans the array, extracts the data, and performs a preliminary data analysis.
  4. The customer receives the raw data, scaled log2-ratio data, p-value data, peaks data (methylated regions), genome annotation, reports listing peaks with associated transcripts and gene annotation information, and complete NimbleGen array design documentation. NimbleGen provides its SignalMap™ Software for visualization of ratio and peak data at no charge with every project.

Sample Requirements

Sample Required 4μg each IP and control samples
Sample Concentration 250-500 ng / μl
Hybridization Volume 15μl
Data Delivery and Data Analysis Tools

Data Delivery

The data delivered with NimbleGen's DNA methylation service includes:

  • Raw data
  • Scaled log2-ratio data
  • P-value GFF file
  • Peaks GFF file
  • SignalMap GFF visualization software
  • Promoter reports mapping DNA methylation to genes

Data sets are provided in GFF file format for easy data set analysis with the SignalMap™ data browser software.

Data Analysis Tools

NimbleGen’s NimbleScan™ software for data extraction provides tools specifically developed for detecting regions of DNA methylation from array data generated using MeDIP or other affinity-based method (such as MBD). For each array, these tools generate a list of methylated regions (peaks) and produce reports that map peaks to specific gene promoters.

NimbleGen’s SignalMap™ data browser enables you to visually interpret the scaled log2-ratio, p-value, and peak data generated by NimbleScan. Graphical representation of your data aids the discovery of epigenetic and transcriptional regulation, including DNA hypermethylation within a target genome and the correlation of promoter and genic methylation with gene expression.

Literature

For a complete listing of literature covering all Roche NimbleGen products and services please visit our literature page.

FAQ
Sample Preparation
What kind of samples can be used on NimbleGen's DNA methylation arrays? These arrays are designed to detect differences between a sample enriched for methylated DNA and a control sample, such as total genomic DNA. We recommend samples enriched using affinity-based methods that utilize an anti-5-mC antibody or MBD proteins. We also accept enzyme based methods to detect DNA methylation, such as Hpa II tiny fragment enrichment by ligation-mediated PCR (HELP).
Do you have a recommended protocol for front-end sample processing for producing DNA fragments enriched for methylation? Yes, we recommend the MeDIP (methylated DNA immunoprecipitation) protocol (Nat Genet. 2005 Aug;37(8):853-62) followed by amplification if necessary. Please contact NimbleGen's Technical Services for a detailed sample preparation protocol.
What is the minimum amount of DNA required to perform a NimbleGen recommended MeDIP experiment? We recommend starting with 5μg high-quality genomic DNA. However, even smaller amount DNA can be used (1μg or even 200ng). The IP process generally yields 5-10% of the original starting DNA, and you can amplify your IP-ed DNA using whole genome amplification (WGA; kit available from Sigma) in order to obtain at least 4μg of DNA.
Do I need to amplify my MeDIP samples? We are able to use unamplified samples for labeling reactions if at least 2.5μg of enriched methylated DNA was obtained. Greater amounts of enriched DNA can be obtained by starting with more DNA and by pooling samples from multiple experiments. If amplifcation is necessary, we recommend using the WGA kit (Sigma, catalog #WGA2-50RXN) for MeDIP samples. We have routinely observed that the WGA method introduces little bias during the amplification.
What is the effect of CpG content on the MeDIP reaction? Studies by Weber et al. (Nat. Genet. 2005, 37(8):853-862) have shown that the more more methylated CpG dinucleotides within a given fragment, the more DNA that is immunoprecipitated. The increase immunoprecipitated material is due to the 5-methylcytidine antibody having more available epitopes (methylated CpG).
What are the sample requirements for DNA methylation arrays? We require 4μg DNA (although 2.5μg is acceptable) at a concentration of 250-500ng/μl with the majority of fragments greater than 200bp. The A260/A280 ratio should be at least 1.7 and the A260/A230 ratio should be at least 1.6.
Does NimbleGen perform front-end sample processing (e.g. IP and amplification)? No, NimbleGen is not currently set up to perform contract DNA methylation experiments for our customers.
Should I use a negative control and if so what should I use? Many of our customers do not use a negative control (e.g. nonspecific IgG antibody), but it is recommended if this is your first experiment with NimbleGen. You will want to have your negative control (IgG) co-hybridized with total DNA (input) in order to avoid a high signal/noise ratio that is often seen when the IgG sample is co-hybridized with the immunoprecipitated sample.
What should I use as a reference sample? The majority of our customers use total (input) sample as a reference. Using a nonspecific IgG is not a suitable reference.
Array Design
Do we have a catalog CpG island array? Yes, we have a CpG island plus promoter array that includes all UCSC annotated CpG islands plus 1kb human promoter or 1.8kb mouse promoter region of every RefSeq gene. Control tiled regions on the array include the HoxA cluster (methylation hotspot) and several imprinted loci, including H19/IGF2, KCNQ1, and IGF2R.
Are the probes designed from both strands? No, NimbleGen only designs probes based off of the forward strand.
How does NimbleGen address repetitive elements in the genome for DNA methylation designs? We have developed our own method of repeat masking which is dependent on the mean frequency of the 15-mers which make up each oligo. A table is made of the count of all 15-mers that appear in the genome, from both strands. Then a 15-mer window is slid along each oligo, looking up the count of each 15-mer in the table, and calculating the average count. A threshold is set, usually 100 for large eukaryotic genomes, and any probe that exceeds that threshold is eliminated from further consideration. Depending on the region of the genome being evaluated, approximately 20-25% of the DNA is excluded. For some designs we use conventional repeat masking, as done by the RepeatMasker program http://www.repeatmasker.org/). However, NimbleGen has no access to the repeat libraries necessary to use this application, so we rely on third parties to supply this type of masked sequence. We find, however, that RepeatMasker is often overly aggressive and can mask 50-55% of human DNA sequence. See the following paper for reference: Bioinformatics. 2006 Jan 15;22(2):134-41. WindowMasker: window-based masker for sequenced genomes; Morgulis A, Gertz EM, Schaffer AA, Agarwala R; National Center for Biotechnology Information, National Institutes of Health, Department of Health and Human Services Building 38A, Room 1003N, 8600 Rockville Pike, Bethesda, MD 20894, USA.
What spacing do you recommend for DNA methylation designs? We recommend probe spacing of 100bp or less.
Can I get a graphical representation of all probes for a cataloged design that I am interested in so I can see what regions of the genome have coverage? Yes, we can generate this information in GFF format for all of catalog designs. You will need a copy of SignalMap to view the GFF files.
Data Analysis
Does NimbleGen normalize DNA methylation data? No, there is no normalization of DNA methylation data. However, we do scale the GFF files by subtracting the bi-weight mean for the log-ratio values from each log-ratio value. This effectively centers the log-ratio values around zero.
How does NimbleGen perform analysis on DNA methylation data? After scaled log2 ratio data is generated a modified ACME algorithm (Method Enzymol. 2006; 411:270-282) is employed where a fixed-length window is slid along the length of each chromosome, testing at each probe using a one-sided Kolmogorov-Smirnov (KS) test whether the surrounding window is enriched for high-intensity probes relative to the rest of the array. Each probe has a corresponding p-value score (-log10) and a threshold is set to select regions that are enriched (i.e. methylated) in the test sample. NimbleScan 2.3 users can download the ACME plug-in by clicking here.
Why is the data analysis for DNA methylation different from ChIP-chip? Since DNA methylation array data is often characterized by broad ranges of enrichment (whereas ChIP-chip data enrichment is more discrete) a different method to identify peaks from scaled log2-ratio data must be employed.
How do I validate a genome-wide DNA methylation array experiment? Common methods include bisulfite sequencing (single nucleotide resolution) to validate methylation status of all CpG dinucleotides within a peak called on the array, combined bisulfite restriction analysis (COBRA, determine percent methylation), and quantitative PCR to validate MeDIP array results by accurately measuring enrichment of methylated DNA fragments.
Deliverables
Can I get the images for my data? Yes, we can supply you with the raw data array images (.tif) upon request. Scaled log2-ratio data (.gff) files and peak (.gff) files are included in your deliverable data along with the visualization software SignalMap.
Can I get a graphical representation of all probes for a cataloged design that I am intersted in so I can see what regions of the genome have coverage? Yes, we can generate this information in GFF format for all of catalog designs. You will need a copy of SignalMap to view the GFF files.
Does NimbleGen generate reports listing the most significant binding/modification events for my DNA methylation experiment? Yes, we are including two summary reports that map the peaks from your DNA methylation data relative to the transcription start site of a gene. For instance, if a peak is called within the promoter region of a gene, the report will give the approximate location of the peak as a negative position (upstream of the start site) or positive position (downstream). Also included are accession number of the gene, gene ID, chromosome position, among others. These reports will help narrow down the genomic regions you should be looking at when moving forward to validate your DNA methylation data (e.g. bisulfite sequencing or qPCR).
Benefits
Why should I use a genome-wide approach to study DNA methylation? NimbleGen's DNA methylation analysis arrays allow you to map DNA methylation across your genome of interest genome in an unbiased fashion, compare differential methylation patterns between cells, tissues, and tumors, and identify prognostic markers.
How sensitive are NimbleGen's DNA methylation arrays? Our arrays, when coupled with MeDIP, can readily detect as little as 2 methylated CpG dinucleotides per fragment.
What is the reproducibility of NimbleGen DNA methylation analysis arrays? While not fully validated by NimbleGen scientists, Weber et al. (Nat. Genet. 2007, 39(4):457-466) observed highly reproducible DNA methylation data between biological replicates (R = 0.92 for WI38 cells and R = 0.95 and 0.91 for sperm) when using MeDIP coupled with NimbleGen human promoter arrays.
Promoter Tiling Arrays
Promoter Tiling Array Designs
Organism: Arabidopsis thaliana
Source: NCBI
Build: TAIR6.0
Probe Length: 50-75mer
Median Probe Spacing 102bp
Probes per Array: 385,000
Feature Size: 16μm x 16μm
Array Dimensions: 17.4mm x 13mm
Overall Slide Dimensions: 1" x 3" (25 x 75mm)
Recommended Storage: Store arrays desiccated at room temperature.
Catalog Number Design Name Description Promoter Upstream Tiling (bp) Promoter Downstream Tiling (bp)
C4499001-00-01 ATH6 min promoter Minimum Promoter Array Design 1200 300
C4496001-00-01 ATH6 promoter 2-Array Set 3000 750
C4497001-01-01 ATH6 promoter 1 of 2 Array 1 of 2 3000 750
C4498001-02-01 ATH6 promoter 2 of 2 Array 2 of 2 3000 750

Organism: Homo sapiens
Source: UCSC
Build: HG18
Probe Length: 50-75mer
Median Probe Spacing: 100bp
Probes per Array: 385,000
Feature Size: 16μm x 16μm
Array Dimensions: 17.4mm x 13mm
Overall Slide Dimensions: 1" x 3" (25 x 75mm)
Recommended Storage: Store arrays desiccated at room temperature.
Catalog Number Design Name Description Promoter Upstream Tiling (bp) Promoter Downstream Tiling (bp)
C4540-SET-01 HG18 promoter 2-Array Set 3500 750
C4540-01-01 HG18 promoter 1 of 2 Array 1 of 2 3500 750
C4540-02-01 HG18 promoter 2 of 2 Array 2 of 2 3500 750
C4226-00-01 HG18 RefSeq promoter   2200 500
C4229-00-01 HG18 RefSeqXM promoter   9000 2000

Organism: Mus musculus
Source: UCSC
Build: MM8
Probe Length:50-75mer
Median Probe Spacing 100bp
Probes per Array: 385,000
Feature Size: 16μm x 16μm
Array Dimensions: 17.4mm x 13mm
Overall Slide Dimensions: 1" x 3" (25 x 75mm)
Recommended Storage: Store arrays desiccated at room temperature.
Catalog Number Design Name Description Promoter Upstream Tiling (bp) Promoter Downstream Tiling (bp)
C3845-SET-02 MM8 promoter 2-Array Set 3250 750
C3845-01-02 MM8 promoter 1 of 2 Array 1 of 2 3250 750
C3845-02-02 MM8 promoter 2 of 2 Array 2 of 2 3250 750
C4222-00-01 MM8 RefSeq promoter   2000 500
C4225-00-01 MM8 RefSeqXM promoter   7000 2000

Organism: Rattus norvegicus
Source: Ensembl
Build: RGSC 3.4
Probe Length: 50-75mer
Median Probe Spacing: 105bp
Probes per Array: 385,000
Feature Size: 16μm x 16μm
Array Dimensions: 17.4mm x 13mm
Overall Slide Dimensions: 1" x 3" (25 x 75mm)
Recommended Storage: Store arrays desiccated at room temperature.
Catalog Number Design Name Description Promoter Upstream Tiling (bp) Promoter Downstream Tiling (bp)
C4492001-00-01 RN34 promoter 2-Array Set 4500 1125
C4493001-01-01 RN34 promoter 1 of 2 Array 1 of 2 4500 1125
C4494001-02-01 RN34 promoter 2 of 2 Array 2 of 2 4500 1125
C4495001-00-01 RN34 RefSeq promoter   2250 500
Promoter plus CpG Island Tiling Array Designs
Probe Length: 50-75mer
Probes per Array: 385,000
Feature Size: 16μm x 16μm
Array Dimensions: 17.4mm x 13mm
Overall Slide Dimensions: 1" x 3" (25 x 75mm)
Recommended Storage: Store arrays desiccated at room temperature.
Catalog Number Design Genome Source Build Number of CpG Islands Promoter Upstream Tiling (bp) Promoter Downstream Tiling (bp)
00892 2006-11-02 HG18 CpG Promoter Homo sapiens UCSC HG18 28226 800 200
00893 2007-02-27 MM8 CpG Promoter Mus musculus UCSC MM8 15963 1300 500
C7120-00-01 080212 RN34 CpG Island Pro Rattus norvegicus Ensembl RGSC 3.4 15809 1300 500
Whole-Genome Tiling Arrays
Arabidopsis thaliana
Source: NCBI
Build: TAIR6.0
Probe Length: 50mer
Median Probe Spacing: 90bp
Accession Numbers: NC_003070,NC_003071,NC_003074,NC_003075,NC_003076
Probes per Array: 385,000
Feature Size: 16μm x 16μm
Array Dimensions: 17.4mm x 13mm
Overall Slide Dimensions: 1" x 3" (25 x 75mm)
Recommended Storage: Store arrays desiccated at room temperature.
Catalog Number Design Name Description Chromosome Tiling Start Tiling Stop
C4348001-SET-01 ATH6 ChIP 3 Array Set Whole Genome Tiling 3-Array Set    
C4348001-01-01 ATH6 ChIP 1 Array 1 of 3 chr1 106 30,432,534
      chr2 1,001 9,687,876
C4348001-02-01 ATH6 ChIP 2 Array 2 of 3 chr2 9,687,916 19,704,755
      chr3 1 23,470,742
      chr4 1,001 6,133,069
C4348001-03-01 ATH6 ChIP 3 Array 3 of 3 chr4 6,133,109 18,584,924
      chr5 1 26,992,695
Canis familiaris
Source: UCSC
Build: canFam2
Probe Length: 50mer
Median Probe Spacing: 100bp
Probes per Array: 385,000
Feature Size: 16μm x 16μm
Array Dimensions: 17.4mm x 13mm
Overall Slide Dimensions: 1" x 3" (25 x 75mm)
Recommended Storage: Store arrays desiccated at room temperature.
Catalog Number Design Name Description Chromosome Tiling Start Tiling Stop
C4529-SET-01 canFam2Tiling Set 37 Array Set Whole Genome Tiling 37-Array Set    
C4529-01-01 canFam2Tiling Set 1 Array 1 of 37 chr1 3,012,394 62,278,628
C4529-02-01 canFam2Tiling Set 2 Array 2 of 37 chr1 62,278,678 125,616,165
      chr2 3,000,001 5,603,265
C4529-03-01 canFam2Tiling Set 3 Array 3 of 37 chr2 5,603,315 69,134,091
C4529-04-01 canFam2Tiling Set 4 Array 4 of 37 chr2 69,134,594 88,407,229
      chr3 3,000,001 48,179,151
C4529-05-01 canFam2Tiling Set 5 Array 5 of 37 chr3 48,179,201 94,714,891
      chr4 3,010,521 18,819,981
C4529-06-01 canFam2Tiling Set 6 Array 6 of 37 chr4 18,820,031 81,540,804
C4529-07-01 canFam2Tiling Set 7 Array 7 of 37 chr4 81,540,854 91,483,852
      chr5 3,009,839 55,204,271
C4529-08-01 canFam2Tiling Set 8 Array 8 of 37 chr5 55,204,321 91,976,388
      chr6 3,015,844 27,099,882
C4529-09-01 canFam2Tiling Set 9 Array 9 of 37 chr6 27,100,060 80,642,094
      chr7 3,000,001 12,088,918
C4529-10-01 canFam2Tiling Set 10 Array 10 of 37 chr7 12,088,968 75,099,510
C4529-11-01 canFam2Tiling Set 11 Array 11 of 37 chr7 75,099,560 83,999,176
      chr8 3,003,063 58,081,791
C4529-12-01 canFam2Tiling Set 12 Array 12 of 37 chr8 58,081,841 77,307,274
      chr9 3,000,001 44,485,970
C4529-13-01 canFam2Tiling Set 13 Array 13 of 37 chr9 44,486,020 64,413,461
      chr10 3,003,191 44,470,365
C4529-14-01 canFam2Tiling Set 14 Array 14 of 37 chr10 44,470,415 72,488,496
      chr11 3,002,836 38,777,021
C4529-15-01 canFam2Tiling Set 15 Array 15 of 37 chr11 38,777,071 77,416,425
      chr12 3,003,326 27,657,072
C4529-16-01 canFam2Tiling Set 16 Array 16 of 37 chr12 27,657,122 75,515,277
      chr13 3,003,109 18,623,175
C4529-17-01 canFam2Tiling Set 17 Array 17 of 37 chr13 18,623,225 66,182,432
      chr14 3,005,181 19,249,997
C4529-18-01 canFam2Tiling Set 18 Array 18 of 37 chr14 19,250,047 63,938,183
      chr15 3,013,266 20,943,569
C4529-19-01 canFam2Tiling Set 19 Array 19 of 37 chr15 20,943,619 67,211,493
      chr16 3,008,838 19,476,430
C4529-20-01 canFam2Tiling Set 20 Array 20 of 37 chr16 19,476,480 62,570,129
      chr17 3,000,001 20,271,895
C4529-21-01 canFam2Tiling Set 21 Array 21 of 37 chr17 20,271,945 67,340,432
      chr18 3,000,001 20,419,229
C4529-22-01 canFam2Tiling Set 22 Array 22 of 37 chr18 20,419,279 58,870,922
      chr19 3,000,001 28,339,210
C4529-23-01 canFam2Tiling Set 23 Array 23 of 37 chr19 28,339,260 56,771,301
      chr20 3,000,001 37,242,822
C4529-24-01 canFam2Tiling Set 24 Array 24 of 37 chr20 37,242,872 61,280,721
      chr21 3,001,882 44,745,333
C4529-25-01 canFam2Tiling Set 25 Array 25 of 37 chr21 44,745,383 54,024,600
      chr22 3,000,919 55,735,714
C4529-26-01 canFam2Tiling Set 26 Array 26 of 37 chr22 55,735,764 64,394,174
      chr23 3,000,001 55,389,494
      chr24 3,000,854 5,202,800
C4529-27-01 canFam2Tiling Set 27 Array 27 of 37 chr24 5,202,850 50,763,049
      chr25 3,000,846 21,376,267
C4529-28-01 canFam2Tiling Set 28 Array 28 of 37 chr25 21,376,317 54,563,572
      chr26 3,007,786 33,257,971
C4529-29-01 canFam2Tiling Set 29 Array 29 of 37 chr26 33,258,021 42,029,628
      chr27 3,000,099 48,905,266
      chr28 3,003,108 12,569,835
C4529-30-01 canFam2Tiling Set 30 Array 30 of 37 chr28 12,569,885 44,190,932
      chr29 3,023,514 33,081,560
C4529-31-01 canFam2Tiling Set 31 Array 31 of 37 chr29 33,081,610 44,828,998
      chr30 3,000,001 43,205,974
      chr31 3,000,365 14,273,595
C4529-32-01 canFam2Tiling Set 32 Array 32 of 37 chr31 14,273,645 42,262,811
      chr32 3,000,482 38,020,796
C4529-33-01 canFam2Tiling Set 33 Array 33 of 37 chr32 38,020,910 41,730,743
      chr33 3,000,001 34,424,222
      chr34 3,000,524 29,859,548
C4529-34-01 canFam2Tiling Set 34 Array 34 of 37 chr34 29,859,598 45,128,234
      chr35 3,000,157 29,533,501
      chr36 3,001,322 22,745,468
C4529-35-01 canFam2Tiling Set 35 Array 35 of 37 chr36 22,745,641 33,840,292
      chr37 3,004,135 33,915,094
      chr38 3,016,144 20,785,825
C4529-36-01 canFam2Tiling Set 36 Array 36 of 37 chr38 20,785,875 26,897,637
      chrX 9 80,254,721
C4529-37-01 canFam2Tiling Set 37 Array 37 of 37 chrM 1 16,694
      chrUn 28,809 86,546,042
      chrX 80,254,771 126,883,716
Gallus gallus
Source: UCSC
Build: galGal3
Probe Length: 50mer
Median Probe Spacing: 100bp
Probes per Array: 385,000
Feature Size: 16μm x 16μm
Array Dimensions: 17.4mm x 13mm
Overall Slide Dimensions: 1" x 3" (25 x 75mm)
Recommended Storage: Store arrays desiccated at room temperature.
Catalog Number Design Name Description Chromosome Tiling Start Tiling Stop
C4530-SET-01 Gal3Tiling Set 27 Array Set Whole Genome Tiling 27-Array Set    
C4530-01-01 Gal3Tiling Set 1 Array 1 of 27 chr1 1 39,473,000
C4530-02-01 Gal3Tiling Set 2 Array 2 of 27 chr1 39,473,050 80,386,539
C4530-03-01 Gal3Tiling Set 3 Array 3 of 27 chr1 80,386,589 119,731,713
C4530-04-01 Gal3Tiling Set 4 Array 4 of 27 chr1 119,731,763 159,240,269
C4530-05-01 Gal3Tiling Set 5 Array 5 of 27 chr1 159,240,319 198,779,897
C4530-06-01 Gal3Tiling Set 6 Array 6 of 27 chr1 198,779,947 200,993,971
      chr1 random 1 222,058
      chr2 1 37,050,048
C4530-07-01 Gal3Tiling Set 7 Array 7 of 27 chr2 37,050,098 77,948,675
C4530-08-01 Gal3Tiling Set 8 Array 8 of 27 chr2 77,948,725 117,274,559
C4530-09-01 Gal3Tiling Set 9 Array 9 of 27 chr2 117,274,609 154,873,711
      chr2 random 1 142,793
      chr3 1 1,760,406
C4530-10-01 Gal3Tiling Set 10 Array 10 of 27 chr3 1,760,456 42,540,444
C4530-11-01 Gal3Tiling Set 11 Array 11 of 27 chr3 42,540,494 81,756,614
C4530-12-01 Gal3Tiling Set 12 Array 12 of 27 chr3 81,756,664 113,657,692
      chr4 39 7,608,274
C4530-13-01 Gal3Tiling Set 13 Array 13 of 27 chr4 7,608,324 48,372,531
C4530-14-01 Gal3Tiling Set 14 Array 14 of 27 chr4 48,372,581 87,660,311
C4530-15-01 Gal3Tiling Set 15 Array 15 of 27 chr4 87,660,361 94,230,338
      chr4 random 1 180,704
      chr5 1 34,275,589
C4530-16-01 Gal3Tiling Set 16 Array 16 of 27 chr5 34,275,639 62,238,856
      chr5 random 1 27,851
      chr6 1,500,001 12,842,108
C4530-17-01 Gal3Tiling Set 17 Array 17 of 27 chr6 12,842,158 37,400,433
      chr6 random 1 34,129
      chr7 1 16,259,739
C4530-18-01 Gal3Tiling Set 18 Array 18 of 27 chr7 16,259,789 38,384,711
      chr7 random 1 103,968
      chr8 1 18,661,092
C4530-19-01 Gal3Tiling Set 19 Array 19 of 27 chr10 1 4,527,828
      chr8 18,661,142 30,671,698
      chr8 random 1 420,684
      chr9 1,500,001 25,554,304
C4530-20-01 Gal3Tiling Set 20 Array 20 of 27 chr10 4,527,878 22,556,366
      chr10 random 1 13,674
      chr11 1 21,928,091
      chr11 random 1 72,609
      chr12 1 110,850
C4530-21-01 Gal3Tiling Set 21 Array 21 of 27 chr12 110,900 20,536,630
      chr12 random 1 7,004
      chr13 500,001 18,911,876
      chr13 random 1 35,727
      chr14 1 1,168,043
C4530-22-01 Gal3Tiling Set 22 Array 22 of 27 chr14 1,168,093 15,819,374
      chr15 1 12,968,127
      chr16 1 432,900
      chr16 random 1 246,201
      chr17 500,001 11,182,467
      chr17 random 1 2,851
      chr18 1 910,609
C4530-23-01 Gal3Tiling Set 23 Array 23 of 27 chr18 910,659 10,925,251
      chr18 random 1 11,883
      chr19 1 9,939,630
      chr20 1 13,986,179
      chr20 random 1 75,038
      chr21 1 5,982,361
C4530-24-01 Gal3Tiling Set 24 Array 24 of 27 chr21 5,982,411 6,959,606
      chr22 1 3,936,495
      chr22 random 1 156,124
      chr23 1 6,042,119
      chr24 1 6,400,030
      chr25 1 2,031,765
      chr25 random 1 80,294
      chr26 1 5,102,354
      chr27 1 4,841,948
      chr28 1 4,511,963
      chr28 random 1 105,400
      chr32 1 951
      chrW 1 259,614
      chrW random 1 729,474
      chrZ 1 7,526,271
C4530-25-01 Gal3Tiling Set 25 Array 25 of 27 chrZ 7,526,321 50,886,328
C4530-26-01 Gal3Tiling Set 26 Array 26 of 27 chrE22C19W28 E50C23 1 895,233
      chrE22C19W28 E50C23 random 1 191,057
      chrE64 1 49,833
      chrE64 random 1 557,616
      chrUn random 1 17,557,610
      chrZ 50,886,378 74,602,257
      chrZ random 1 346,154
C4530-27-01 Gal3Tiling Set 27 Array 27 of 27 chrUn random 17,557,660 63,870,725
ENCODE
General Array Specs
Probes per Array: 385,000
Feature Size: 16μm x 16μm
Array Size: 17.4mm x 13mm
Slide Size: 1" x 3" (25 x 75mm)
Recommended Storage: Desiccated at room temperature.
Organism: Homo sapiens
Source: UCSC
Build: HG17
Catalog Number Design Name Description Chromosome Probe Length Median Probe Spacing
C1980001-00-01 HG17 ENCODE 50mer Array 1 of 1 Tiles All ENCODE Regions 50mer 38bp
Organism: Homo sapiens
Source: UCSC
Build: HG18
Catalog Number Design Name Description Chromosome Probe Length Median Probe Spacing
C6709-00-01 HG18 ENCODE Array 1 of 1 Tiles All ENCODE Regions 50-75mer 60bp
Organism: Canis familiaris
Source: UCSC
Build: CF2
Catalog Number Design Name Description Chromosome Probe Length Median Probe Spacing
C3077-00-01 CF2 ENCODE Array 1 of 1 Tiles All ENCODE Regions 50mer 45bp
Homo sapiens
Source: UCSC
Build: HG18
Probe Length: 50mer
Median Probe Spacing: 100bp
Probes per Array: 385,000
Feature Size: 16μm x 16μm
Array Dimensions: 17.4mm x 13mm
Overall Slide Dimensions: 1" x 3" (25 x 75mm)
Recommended Storage: Store arrays desiccated at room temperature.
Catalog Number Design Name Description Chromosome Tiling Start Tiling Stop
C4524-SET-01 HG18Tiling Set 38 Array Set Whole Genome 38-Array Set    
C4524-01-01 HG18Tiling Set 1 Array 1 of 38 chr1 1,644 77,833,868
C4524-02-01 HG18Tiling Set 2 Array 2 of 38 chr1 77,833,918 175,048,429
C4524-03-01 HG18Tiling Set 3 Array 3 of 38 chr1 175,050,895 247,197,901
      chr1 random 1,609 1,660,118
      chr2 2,789 166,769
C4524-04-01 HG18Tiling Set 4 Array 4 of 38 chr2 166,819 71,983,140
C4524-05-01 HG18Tiling Set 5 Array 5 of 38 chr2 71,983,425 150,976,181
C4524-06-01 HG18Tiling Set 6 Array 6 of 38 chr2 150,976,231 221,986,862
C4524-07-01 HG18Tiling Set 7 Array 7 of 38 chr2 221,986,912 242,751,051
      chr2 random 1 185,538
      chr3 35,001 53,042,567
C4524-08-01 HG18Tiling Set 8 Array 8 of 38 chr3 53,043,153 130,523,638
C4524-09-01 HG18Tiling Set 9 Array 9 of 38 chr3 130,523,688 199,446,729
      chr3 random 1,180 749,171
      chr4 6,124 5,907,785
C4524-10-01 HG18Tiling Set 10 Array 10 of 38 chr4 5,907,836 86,895,691
C4524-11-01 HG18Tiling Set 11 Array 11 of 38 chr4 86,895,741 162,579,935
C4524-12-01 HG18Tiling Set 12 Array 12 of 38 chr4 162,580,158 191,260,272
      chr4 random 1 842,645
      chr5 64,882 43,102,632
C4524-13-01 HG18Tiling Set 13 Array 13 of 38 chr5 43,102,682 120,977,621
C4524-14-01 HG18Tiling Set 14 Array 14 of 38 chr5 120,977,671 180,836,772
      chr5 random 700 141,287
      chr6 5,001 14,400,058
C4524-15-01 HG18Tiling Set 15 Array 15 of 38 chr6 14,400,108 93,424,260
C4524-16-01 HG18Tiling Set 16 Array 16 of 38 chr6 93,424,310 165,905,673
C4524-17-01 HG18Tiling Set 17 Array 17 of 38 chr6 165,905,853 170,896,928
      chr6 random 723 1,875,488
      chr7 34,001 71,893,449
C4524-18-01 HG18Tiling Set 18 Array 18 of 38 chr7 71,893,499 146,115,149
C4524-19-01 HG18Tiling Set 19 Array 19 of 38 chr7 146,115,199 158,821,243
      chr7 random 66 547,244
      chr8 1 64,734,981
C4524-20-01 HG18Tiling Set 20 Array 20 of 38 chr8 64,735,105 139,834,728
C4524-21-01 HG18Tiling Set 21 Array 21 of 38 chr8 139,834,778 146,273,006
      chr8 random 2,645 943,766
      chr9 1,894 87,382,297
C4524-22-01 HG18Tiling Set 22 Array 22 of 38 chr10 50,001 19,976,990
      chr9 87,382,347 140,272,350
      chr9 random 1,524 1,146,418
C4524-23-01 HG18Tiling Set 23 Array 23 of 38 chr10 19,977,040 99,783,066
C4524-24-01 HG18Tiling Set 24 Array 24 of 38 chr10 99,783,524 135,370,851
      chr10 random 899 113,241
      chr11 50,001 35,341,402
C4524-25-01 HG18Tiling Set 25 Array 25 of 38 chr11 35,341,452 117,277,977
C4524-26-01 HG18Tiling Set 26 Array 26 of 38 chr11 117,278,030 134,450,373
      chr11 random 1 215,264
      chr12 17,430 58,836,794
C4524-27-01 HG18Tiling Set 27 Array 27 of 38 chr12 58,836,844 132,289,483
      chr13 17,918,001 22,162,992
C4524-28-01 HG18Tiling Set 28 Array 28 of 38 chr13 22,163,047 95,001,767
C4524-29-01 HG18Tiling Set 29 Array 29 of 38 chr13 95,001,817 114,127,886
      chr13 random 1 186,280
      chr14 18,126,852 72,700,758
C4524-30-01 HG18Tiling Set 30 Array 30 of 38 chr14 72,700,808 106,360,511
      chr15 18,303,911 58,530,389
C4524-31-01 HG18Tiling Set 31 Array 31 of 38 chr15 58,530,439 100,336,874
      chr15 random 1 784,326
      chr16 1,462 32,788,140
C4524-32-01 HG18Tiling Set 32 Array 32 of 38 chr16 32,788,379 88,820,540
      chr16 random 485 105,474
      chr17 1 28,580,036
C4524-33-01 HG18Tiling Set 33 Array 33 of 38 chr17 28,580,086 78,654,701
      chr17 random 1 2,617,362
      chr18 1,146 22,939,995
C4524-34-01 HG18Tiling Set 34 Array 34 of 38 chr18 22,940,045 76,116,085
      chr18 random 1 4,250
      chr19 11,001 19,529,590
C4524-35-01 HG18Tiling Set 35 Array 35 of 38 chr19 19,529,928 63,805,962
      chr19 random 8,246 301,805
      chr20 11,165 50,138,814
C4524-36-01 HG18Tiling Set 36 Array 36 of 38 chr20 50,138,864 62,432,160
      chr21 9,882,592 46,941,530
      chr21 random 1,024 1,679,609
      chr22 14,430,066 39,529,828
C4524-37-01 HG18Tiling Set 37 Array 37 of 38 chr22 39,529,878 49,590,841
      chr22 random 1 257,295
      chrX 447 85,044,437
C4524-38-01 HG18Tiling Set 38 Array 38 of 38 chrM 1 16,477
      chrX 85,044,487 154,911,115
      chrX random 1 1,718,128
      chrY 447 57,770,315
Mus musculus
Source: UCSC
Build: MM8
Probe Length: 50mer
Median Probe Spacing: 100bp
Probes per Array: 385,000
Feature Size: 16μm x 16μm
Array Dimensions: 17.4mm x 13mm
Overall Slide Dimensions: 1" x 3" (25 x 75mm)
Recommended Storage: Store arrays desiccated at room temperature.
Catalog Number Design Name Description Chromosome Tiling Start Tiling Stop
C4527-SET-01 MM8Tiling Set 38 Array Set Whole Genome 38-Array Set    
C4527-01-01 MM8Tiling Set 1 Array 1 of 38 chr1 3,000,157 73,220,987
C4527-02-01 MM8Tiling Set 2 Array 2 of 38 chr1 73,221,037 145,835,677
C4527-03-01 MM8Tiling Set 3 Array 3 of 38 chr1 145,835,727 197,066,777
      chr1 random 102 172,125
      chr2 3,006,246 14,803,550
C4527-04-01 MM8Tiling Set 4 Array 4 of 38 chr2 14,803,600 78,803,469
C4527-05-01 MM8Tiling Set 5 Array 5 of 38 chr2 78,803,519 144,694,967
C4527-06-01 MM8Tiling Set 6 Array 6 of 38 chr2 144,695,017 181,926,733
      chr3 3,000,001 35,945,810
C4527-07-01 MM8Tiling Set 7 Array 7 of 38 chr3 35,946,023 105,538,217
C4527-08-01 MM8Tiling Set 8 Array 8 of 38 chr3 105,538,373 159,872,029
      chr4 3,006,467 13,466,829
C4527-09-01 MM8Tiling Set 9 Array 9 of 38 chr4 13,466,879 86,052,953
C4527-10-01 MM8Tiling Set 10 Array 10 of 38 chr4 86,053,003 151,907,497
C4527-11-01 MM8Tiling Set 11 Array 11 of 38 chr4 151,907,547 155,029,701
      chr5 3,002,590 66,825,929
C4527-12-01 MM8Tiling Set 12 Array 12 of 38 chr5 66,825,979 132,198,192
C4527-13-01 MM8Tiling Set 13 Array 13 of 38 chr5 132,198,242 152,002,824
      chr5 random 1 2,921,181
      chr6 3,000,336 49,711,116
C4527-14-01 MM8Tiling Set 14 Array 14 of 38 chr6 49,711,166 116,290,338
C4527-15-01 MM8Tiling Set 15 Array 15 of 38 chr6 116,290,495 149,525,670
      chr7 3,002,498 47,370,177
C4527-16-01 MM8Tiling Set 16 Array 16 of 38 chr7 47,370,227 115,300,979
C4527-17-01 MM8Tiling Set 17 Array 17 of 38 chr7 115,301,029 145,133,805
      chr7 random 152 243,780
      chr8 3,000,187 37,161,130
C4527-18-01 MM8Tiling Set 18 Array 18 of 38 chr8 37,161,180 106,292,103
C4527-19-01 MM8Tiling Set 19 Array 19 of 38 chr8 106,292,153 132,084,079
      chr8 random 1 206,881
      chr9 3,038,420 43,286,226
C4527-20-01 MM8Tiling Set 20 Array 20 of 38 chr9 43,286,276 105,899,668
C4527-21-01 MM8Tiling Set 21 Array 21 of 38 chr10 3,002,171 52,787,705
      chr9 105,899,718 123,997,618
      chr9 random 1 16,735
C4527-22-01 MM8Tiling Set 22 Array 22 of 38 chr10 52,787,755 117,084,713
C4527-23-01 MM8Tiling Set 23 Array 23 of 38 chr10 117,084,763 129,952,011
      chr10 random 1 10,464
      chr11 3,005,467 56,613,072
C4527-24-01 MM8Tiling Set 24 Array 24 of 38 chr11 56,613,122 117,015,745
C4527-25-01 MM8Tiling Set 25 Array 25 of 38 chr11 117,015,795 121,798,318
      chr12 3,000,001 66,136,890
C4527-26-01 MM8Tiling Set 26 Array 26 of 38 chr12 66,136,940 120,463,116
      chr13 3,001,731 13,478,312
C4527-27-01 MM8Tiling Set 27 Array 27 of 38 chr13 13,478,362 79,149,705
C4527-28-01 MM8Tiling Set 28 Array 28 of 38 chr13 79,149,801 120,614,368
      chr13 random 1 436,142
      chr14 3,000,283 28,012,624
C4527-29-01 MM8Tiling Set 29 Array 29 of 38 chr14 28,012,674 95,499,352
C4527-30-01 MM8Tiling Set 30 Array 30 of 38 chr14 95,499,402 123,975,857
      chr15 3,001,925 42,329,373
C4527-31-01 MM8Tiling Set 31 Array 31 of 38 chr15 42,329,489 103,492,126
      chr15 random 1 105,912
      chr16 3,001,091 5,125,906
C4527-32-01 MM8Tiling Set 32 Array 32 of 38 chr16 5,126,120 71,871,524
C4527-33-01 MM8Tiling Set 33 Array 33 of 38 chr16 71,871,574 98,252,249
      chr17 3,000,366 42,700,654
C4527-34-01 MM8Tiling Set 34 Array 34 of 38 chr17 42,700,704 95,177,193
      chr17 random 59 88,343
      chr18 3,000,001 18,021,916
C4527-35-01 MM8Tiling Set 35 Array 35 of 38 chr18 18,021,966 81,920,670
C4527-36-01 MM8Tiling Set 36 Array 36 of 38 chr18 81,920,720 90,736,043
      chr19 3,000,194 58,910,586
C4527-37-01 MM8Tiling Set 37 Array 37 of 38 chr19 58,910,636 61,321,095
      chrX 3,007,927 93,883,916
C4527-38-01 MM8Tiling Set 38 Array 38 of 38 chrM 1 16,293
      chrUn random 719 1,539,820
      chrX 93,883,966 165,556,020
      chrX random 342 39,608
      chrY 1 2,728,984
      chrY random 6,952 14,577,665
Rattus norvegicus
Source: UCSC
Build: RN3
Probe Length: 50mer
Median Probe Spacing: 100bp
Probes per Array: 385,000
Feature Size: 16μm x 16μm
Array Dimensions: 17.4mm x 13mm
Overall Slide Dimensions: 1" x 3" (25 x 75mm)
Recommended Storage: Store arrays desiccated at room temperature.
Catalog Number Design Name Description Chromosome Tiling Start Tiling Stop
C4528-SET-01 RN3Tiling Set 37 Array Set Whole Genome 37-Array Set    
C4528-01-01 RN3Tiling Set 1 Array 1 of 37 chr1 5,520 79,919,584
C4528-02-01 RN3Tiling Set 2 Array 2 of 37 chr1 79,919,634 154,041,905
C4528-03-01 RN3Tiling Set 3 Array 3 of 37 chr1 154,041,955 224,172,034
C4528-04-01 RN3Tiling Set 4 Array 4 of 37 chr1 224,172,084 267,910,880
      chr2 1 31,354,399
C4528-05-01 RN3Tiling Set 5 Array 5 of 37 chr2 31,354,517 109,576,919
C4528-06-01 RN3Tiling Set 6 Array 6 of 37 chr2 109,576,969 185,872,738
C4528-07-01 RN3Tiling Set 7 Array 7 of 37 chr2 185,872,788 256,774,166
C4528-08-01 RN3Tiling Set 8 Array 8 of 37 chr2 256,774,216 258,200,683
      chr3 1 68,062,290
C4528-09-01 RN3Tiling Set 9 Array 9 of 37 chr3 68,062,340 139,490,656
C4528-10-01 RN3Tiling Set 10 Array 10 of 37 chr3 139,490,706 171,063,075
      chr4 3,118 39,789,881
C4528-11-01 RN3Tiling Set 11 Array 11 of 37 chr4 39,789,931 115,751,389
C4528-12-01 RN3Tiling Set 12 Array 12 of 37 chr4 115,751,720 184,999,983
C4528-13-01 RN3Tiling Set 13 Array 13 of 37 chr4 185,000,037 187,125,250
      chr5 5,760 77,486,463
C4528-14-01 RN3Tiling Set 14 Array 14 of 37 chr5 77,486,513 151,080,950
C4528-15-01 RN3Tiling Set 15 Array 15 of 37 chr5 151,081,000 173,096,189
      chr6 5,572 47,549,369
C4528-16-01 RN3Tiling Set 16 Array 16 of 37 chr6 47,549,419 121,154,039
C4528-17-01 RN3Tiling Set 17 Array 17 of 37 chr6 121,154,089 147,630,634
      chr7 6,203 47,765,412
C4528-18-01 RN3Tiling Set 18 Array 18 of 37 chr7 47,765,462 117,227,981
C4528-19-01 RN3Tiling Set 19 Array 19 of 37 chr7 117,228,031 143,002,625
      chr8 3,406 46,729,790
C4528-20-01 RN3Tiling Set 20 Array 20 of 37 chr8 46,729,840 113,494,580
C4528-21-01 RN3Tiling Set 21 Array 21 of 37 chr8 113,494,630 129,041,631
      chr9 2,845 56,983,099
C4528-22-01 RN3Tiling Set 22 Array 22 of 37 chr10 1 10,356,380
      chr9 56,983,149 113,440,438
C4528-23-01 RN3Tiling Set 23 Array 23 of 37 chr10 10,361,275 76,932,657
C4528-24-01 RN3Tiling Set 24 Array 24 of 37 chr10 76,932,707 110,718,830
      chr11 5,213 34,964,213
C4528-25-01 RN3Tiling Set 25 Array 25 of 37 chr11 34,964,263 87,757,544
      chr12 1 19,861,316
C4528-26-01 RN3Tiling Set 26 Array 26 of 37 chr12 19,861,366 46,782,087
      chr13 1 53,625,008
C4528-27-01 RN3Tiling Set 27 Array 27 of 37 chr13 53,625,058 111,151,398
      chr14 1,899 12,118,032
C4528-28-01 RN3Tiling Set 28 Array 28 of 37 chr14 12,118,082 85,664,357
C4528-29-01 RN3Tiling Set 29 Array 29 of 37 chr14 85,664,970 112,194,154
      chr15 1,104 46,654,817
C4528-30-01 RN3Tiling Set 30 Array 30 of 37 chr15 46,655,396 109,756,002
      chr16 1 8,