• Roche NimbleGen Probe Design Fundamentals
  Technical Note (PDF Format 149KB)

General Documents

• NimbleGen Sequence Capture
  Brochure (PDF Format 2MB)
• NimbleGen Array Capture Outperforms Two Target-Enrichment Methods in ABRF Research Group Comparison
  Reprint - GenomeWeb InSequence (PDF Format 107KB)
• Comparison of Enrichment Technologies for Targeted Resequencing of Custom Regions
  Technical Note (PDF Format 552KB)
• Sequence Capture Custom Designs: Guide to Submitting Your Target Sequence
  User’s Guide (PDF Format 906KB)

SeqCap EZ Exome Documents

• SeqCap EZ Exome Library & 454 GS FLX Titanium Series
  Sales Flyer (PDF Format 1.5MB)
• SeqCap EZ Exome Library LR
  User’s Guide (PDF Format 712KB)
• SeqCap EZ Exome for Short Read Sequencing
  Sales Flyer (PDF Format 1.1MB)
• SeqCap EZ Exome Library SR (Version 1.2)
  User’s Guide (PDF Format 1.4MB)

Delivery Workflow Documents

• NimbleGen 454 Optimized Sequence Capture 385K Arrays
  Sales Flyer (PDF Format 473KB)
• NimbleGen Sequence Capture 2.1M Human Exome Array
  Sales Flyer (PDF Format 977KB)
• NimbleGen Sequence Capture 385K Version 2.0 Arrays: Custom Human Arrays for Delivery
  Sales Flyer (PDF Format 309KB)
• NimbleGen Sequence Capture 2.1M and 385K Arrays: Equipment and Reagent Requirements
  Sales Flyer (PDF Format 247KB)
• NimbleGen Arrays User’s Guide: 454 Optimized Sequence Capture Array Delivery (Version 1.1)
  User’s Guide (PDF Format 1.3MB)
• NimbleGen Arrays User’s Guide: Sequence Capture Array Delivery (Version 3.2)
  User’s Guide (PDF Format 3.4MB)
• 2.1M Human Exome Annotation Files
  Annotation Files (ZIP Format 8.7MB)
  What files are included in this download?

Service Workflow Documents

• NimbleGen Sequence Capture - Full Service Solution
  Sales Flyer (PDF Format 275KB)
• NimbleGen Services User’s Guide: Sequence Capture Service (Version 3.0)
  User’s Guide (PDF Format 2.2MB)
• NimbleGen Sequence Capture 2.1M Human Exome Array
  Sales Flyer (PDF Format 977KB)

Brochures & Datasheets

• NimbleGen Copy Number Variation (CNV) Arrays
  Datasheet (PDF Format 1.4MB)
• NimbleGen Human CGH Whole-Genome Arrays
  Brochure (PDF Format 2.2MB)

User Guides

• NimbleGen Arrays User’s Guide: CGH and CNV Arrays (Version 7.0)
  User’s Guide (PDF Format 4.7MB)
• NimbleGen Arrays User’s Guide: CGX Arrays (Version 2.0)
  User’s Guide (PDF Format 5.7MB)

Downloads

• Descriptions of HG18 Annotation Files
  Datasheet (PDF Format 49KB)
• Human Genome HG18 Annotation Files
  Annotation Files (ZIP Format 11.2MB)
  What files are included in this download?

Application Notes & Whitepapers

• Array CGH using DNA from Formalin-Fixed Paraffin-Embedded (FFPE) Tissue Samples
  Technical Note (PDF Format 2MB)
• Detecting Copy Number Variants Associated with Basal Cell Carcinoma in an Arsenic-Exposed Population
  Application Note (PDF Format 1.2MB)
• High Resolution Copy Number Analysis of Parkinson’s Samples Using Nexus Copy Number and Roche NimbleGen Microarrays
  Whitepaper (PDF Format 964KB)

Brochures & Datasheets

• NimbleGen ChIP-chip & DNA Methylation Microarrays
  Brochure (PDF Format 2.6MB)
• NimbleGen ChIP-chip 4x72K Array Delivery
  Datasheet (PDF Format 256KB)
• NimbleGen ChIP-chip 2.1M Whole-Genome Tiling and Deluxe Promoter Array Delivery
  Datasheet (PDF Format 419KB)

User Guides

• NimbleGen Arrays User’s Guide: ChIP-chip Analysis (Version 6.1)
  User’s Guide (PDF Format 4.8MB)
• Guide to Identifying Motifs from Your ChIP-chip Data
  CEAS User’s Guide (PDF Format 108KB)
  Find out more about CEAS...
• Guide to Functionally Annotating Your ChIP-chip Data
  DAVID User’s Guide (PDF Format 274KB)
  Find our more about DAVID...

Downloads

• 385K HG18 Tiled Promoters
  List of HG18 genes whose promoters are tiled on 385K Promoter Arrays (Excel Format 13.2MB)
• 385K MM8 Tiled Promoters
  List of MM8 genes whose promoters are tiled on 385K Promoter Arrays (Excel Format 11.3MB)

Application Notes & Whitepapers

• Frequent switching of Polycomb repressive marks and DNA hypermethylation in the PC3 prostate cancer cell line
  Application Note (PDF Format 914KB)
• Using Chromatin Immunoprecipitations (ChIP) to Determine Protein Binding Sites on DNA
  Whitepaper (PDF Format 436KB)

Brochures & Datasheets

• NimbleGen ChIP-chip & DNA Methylation Microarrays
  Brochure (PDF Format 2.6MB)
• NimbleGen DNA Methylation 2.1M Whole-genome Tiling and Deluxe Promoter Arrays
  Datasheet (PDF Format 1.4MB)
• NimbleGen DNA Methylation 4x72K Array Delivery
  Datasheet (PDF Format 312KB)

User Guides

• NimbleGen Arrays User’s Guide: DNA Methylation Analysis (Version 7.1)
  User’s Guide (PDF Format 4.8MB)
• Guide to Functionally Annotating Your DNA Methylation Data (Version 1.2)
  DAVID User’s Guide (PDF Format 274KB)
  Find our more about DAVID...

Downloads

• 385K HG18 Tiled Promoters
  List of HG18 genes whose promoters are tiled on 385K Promoter Arrays (Excel Format 13.2MB)
• 385K MM8 Tiled Promoters
  List of MM8 genes whose promoters are tiled on 385K Promoter Arrays (Excel Format 11.3MB)

Application Notes & Whitepapers

• Frequent switching of Polycomb repressive marks and DNA hypermethylation in the PC3 prostate cancer cell line
  Application Note (PDF Format 914KB)
• Genome-Wide Screen of Promoter Methylation Identifies Novel Markers in Melanoma
  Application Note (PDF Format 2.7MB)

Brochures & Datasheets

• NimbleGen Gene Expression Microarrays and Services
  Brochure (PDF Format 1MB)
• NimbleGen Gene Expression 12x135K Arrays
  Datasheet (PDF Format 276KB)
• NimbleGen Prokaryotic Gene Expression 4x72K Microarrays
  Datasheet (PDF Format 480KB)
• NimbleGen Zebrafish Gene Expression 385K Arrays
  Datasheet (PDF Format 361KB)

User Guides

• NimbleGen Arrays User’s Guide: Gene Expression Analysis (Version 5.0)
  User’s Guide (PDF Format 5.4MB)

Application Notes & Technical Notes

• Genome-Wide Screen of Promoter Methylation Identifies Novel Markers in Melanoma
  Application Note (PDF Format 2.7MB)
• High-Quality Data Obtained with NimbleGen Gene Expression Arrays
  Technical Note (PDF Format 125KB)

• NimbleGen CGS Microarrays and Services
  Datasheet (PDF Format 1.2MB)

MS 200 Microarray Scanner

• NimbleGen MS 200 Microarray Scanner
  Brochure (PDF Format 1.4MB)
• NimbleGen MS 200 Microarray Scanner
  Datasheet (PDF Format 458KB)
• NimbleGen MS 200 Microarray Scanner Operator’s Manual (Version 1.0)
  Operator's Manual (PDF Format 12.62MB)
• NimbleGen MS 200 Data Collection Software v1.1
  Release Notes (PDF Format 101KB)
• NimbleGen MS 200 Microarray Scanner: Agilent 1x1M Array Feature Extraction
  Technical Note (PDF Format 1.3MB)

Hybridization System

• NimbleGen Hybridization System User's Guide (Version 1.5)
  User’s Guide (PDF Format 1MB)
• NimbleGen Hybridization System Unpacking and Installation Instructions (Version 3.0)
  Installation Note (PDF Format 70KB)
• NimbleGen Hybridization System Outperforms Rotating Hybridization Wheel
  Technical Note (PDF Format 252KB)

Microarray Dryer

• NimbleGen Microarray Dryer
  Datasheet (PDF Format 296KB)
• NimbleGen Microarray Dryer Operator’s Manual (Version 1.0)
  Operator's Manual (PDF Format 3.69MB)

Datasheets

• NimbleGen Microarray Processing Reagents
  Datasheet (PDF Format 170KB)
• NimbleGen Dual-Color DNA Labeling Kit
  Datasheet (PDF Format 669KB)
• NimbleGen One-Color DNA Labeling Kit
  Datasheet (PDF Format 1.3MB)

Sample Labeling Instructions

• NimbleGen Comparative Genomic Hybridization (CGH) Microarrays
  Sample Labeling Instructions (PDF Format 141KB)
• NimbleGen Chromatin Immunoprecipitation-on-chip (ChIP-chip) Microarrays
  Sample Labeling Instructions (PDF Format 150KB)
• NimbleGen DNA Methylation Microarrays
  Sample Labeling Instructions (PDF Format 141KB)
• NimbleGen Expression Microarrays
  Sample Labeling Instructions (PDF Format 150KB)

• NimbleScan Software User’s Guide: Version 2.6
  User’s Guide (PDF Format 5.8MB)
• NimbleScan v2.6 Software
  Release Notes (PDF Format 112KB)
• SignalMap v1.9 User’s Guide
  User’s Guide (PDF Format 835KB)

• 1M DTT
  Material Safety Datasheet (PDF Format 90KB)
• 2X Hybridization Buffer
  Material Safety Datasheet (PDF Format 90KB)
• 2X Stringent Wash
  Material Safety Datasheet (PDF Format 89KB)
• 10X Wash Buffer I
  Material Safety Datasheet (PDF Format 91KB)
• 10X Wash Buffer II
  Material Safety Datasheet (PDF Format 90KB)
• 10X Wash Buffer III
  Material Safety Datasheet (PDF Format 90KB)
• Acetonitrile
  Material Safety Datasheet (PDF Format 105KB)
• DCI Activator
  Material Safety Datasheet (PDF Format 110KB)
• Exposure Solvent
  Material Safety Datasheet (PDF Format 96KB)
• Hyb Component A
  Material Safety Datasheet (PDF Format 96KB)
• Oxidizer
  Material Safety Datasheet (PDF Format 106KB)