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Roche NimbleGen Instruments Roche NimbleGen now presents a complete, optimized workflow for NimbleGen DNA microarrays. This optimized workflow encompasses high-density NimbleGen arrays, 4-Bay and 12-Bay Hybridization Systems, Microarray Dryer, MS 200 Microarray Scanner, NimbleScan and SignalMap software , and a comprehensive range of kits and consumables to facilitate processing of NimbleGen DNA microarrays from hybridization through data analysis. 
The NimbleGen MS 200 Microarray Scanner (shown at right) is the first scanner optimized to unleash the full potential and capture the complete picture from NimbleGen DNA microarrays. The MS 200 offers 2 micron resolution and heightened sensitivity to achieve high data quality and confident results from high-density NimbleGen microarrays of today and tomorrow. Critical to the the workflow, NimbleScan and SignalMap software are included to analyze and view the high-quality data from the MS 200. High-throughput genomics research is now possible with the MS 200’s automated features, which are specifically designed for the NimbleGen microarray workflow. Advanced features such as a 48-slide autoloader, integrated barcode reader, autofocus, and auto gain combine to offer walkaway automation, allowing you to focus on your science. For the complete list of advantages and supporting technical figures please visit the MS 200 Microarray Scanner page. Ordering Information
Specifications
A Roche NimbleGen Hybridization System is your lab’s next step in increasing throughput while achieving consistent and reproducible microarray hybridization results. This easy-to-use system provides an active mixing action and constant incubation temperature to improve hybridization uniformity and enhance signal. Its robust and proven design ensures smooth operation every time, while its modular framework facilitates rapid scaleup of your microarray experiments. Choose between the 4-bay model (shown at right) or the 12-bay model (shown at top of page) to meet the throughput demands of your lab, utilizing just one bay or all of them as your day-to-day needs dictate. Specifications
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Effective washing and complete removal of wash solution prior to scanning is critically important when processing DNA microarrays. Salt crystallization and other residue formations resulting from insufficient washing or removal of wash solution can compromise vital data, contribute to high background signal, or both. Additionally, protection of the hybridized array from environmental degradation during the wet-to-dry transition is essential to maintain fluorescent signal. The NimbleGen Microarray Dryer helps to ensure production of high-quality images with minimal residue without the use of noxious chemicals, such as acetonitrile. The array drying step is performed in a protected environment to reduce atmospheric and light-induced degradation of Cy dyes. A key component of the NimbleGen microarray workflow, the NimbleGen Microarray Dryer is used with NimbleGen Hybridization Systems, Mixers, and Wash Buffer Kits to provide the complete array processing solution for NimbleGen DNA Microarrays. Ordering Information
Specifications
The NimbleGen Elution System (shown at right) is used in conjunction with an Elution Chamber (provided separately with each NimbleGen Sequence Capture array) to facilitate the elution of enriched DNA from the surface of a NimbleGen Sequence Capture array following hybridization and washing procedures. Please refer to the NimbleGen Arrays User’s Guide: Sequence Capture Array Delivery (Version 2.0) for more details). The Elution System Retaining Ring secures the Elution Chamber and array firmly against the surface of the Elution System Base, while the Elution System Base conducts heat to the array surface to release captured DNA from the oligonucleotide probes and into solution. NimbleGen Elution System Components
Roche NimbleGen Mixers, which you adhere directly to microarray slides before sample loading and hybridization, are a key component of the NimbleGen Hybridization System. The Mixers allow for a 3-fold reduction of hybridization volume, leading to greater sensitivity and reliable results while economizing on sample requirements. They fit NimbleGen arrays precisely and have been optimized for NimbleGen array dimensions, ensuring uniform signal and high sensitivity with minimal sample volume. Advantages
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