Roche NimbleGen | Products & Services

Products & Services

Roche NimbleGen is working with scientists on the genomic frontier to develop and deploy a wide range of new microarray applications. These advanced array applications all leverage Roche NimbleGen's unique ability to make oligo arrays with high density, extreme flexibility, long oligo probes, and very short design times. Moving beyond expression of known genes or genotyping collections of SNPs, the genomic frontier includes a variety of novel approaches to the study of genetic variation.

What Products Do We Offer?

Sequence Capture - Enrich thousands of targeted loci from complex genomic DNA for high-throughput sequencing with programmable Sequence Capture microarrays.
Array CGH - Identify genomic insertions and deletions and copy number changes at ultra-high resolution, genome wide or focused fine tiling, with high-definition CGH.
ChIP-chip - Map regulatory protein binding sites genome wide for transcription factors, polymerases and histones, or target promoter regions with ChIP-chip analysis.
DNA Methylation - Find methylated regions genome-wide or within targeted promoters or CpG islands with NimbleGen's high-resolution DNA methylation analysis technology.
Gene Expression - Determine differentially expressed genes and map transcription activity with prokaryotic or eukaryotic whole-genome expression analysis.
Comparative Genome Sequencing - Survey microbial genomes and identify and categorize all SNPs in a single experiment with Comparative Genome Sequencing.

How Can We Best Serve You?

Do you...		We Offer
	...want us to do the work for you?	NimbleGen Service
	...work in a lab equipped to run DNA microarrays?	NimbleGen Arrays

What's Better About Our Arrays?

Unmatched density. The NimbleGen technology supports unmatched probe density - up to 390,000 probes/array - in addition to the ability to empirically select probes.
Unprecedented flexibility. Roche NimbleGen provides you the ultimate flexibility in designing and customizing arrays. You can cluster probes to create features of different spot sizes and oligonucleotide lengths - from 24mers up to 70mers, in any configuration - to best fit your needs. Plus, you'll find it easy to modify an existing array design.
Reduced time. The NimbleGen system dramatically cuts the time to create custom array designs from as long as six months to just a few hours, substantially reducing development time and costs.
Highest quality. NimbleGen technology improves in situ synthesis to create high-quality arrays with reproducible (r^2>=0.99) and consistent results.
Lower costs. NimbleGen technology eliminates the high upfront costs for custom, high-density array development. Instead of physically manufactured masks, a digital computer file controls the micromirrors that create the array. This technology dramatically cuts the upfront cost of array design, thus enabling low cost, short manufacturing runs.