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| Recent Webinars |
A. Leonardo Iniguez, Ph. D.
Senior Scientist, Epigenetics
Roche NimbleGen
Madison, WI |
Thursday, November 6, 2008 |
Introducing NimbleGen HD2 Arrays for High-Resolution ChIP-chip Analysis
ChIP-chip is a powerful technique that allows for the high resolution mapping of chromatin structure including histone modifications, transcription factor and nucleic acid polymerase binding, nucleosome location, and DNase I hypersensitivity. Roche NimbleGen, the leading platform for ChIP-chip, is proud to introduce HD2 (2.1 million probes) arrays for delivery and service. NimbleGen ChIP-chip HD2 arrays now provide more than a 5-fold increase in probe density per array, which allows for increasing the coverage of key biological features, such as promoters and CpG islands, and decreasing the number of arrays needed to perform whole genome analysis at high resolution. This increase in probe density has been implemented in a number of catalog designs, including whole genome and promoter specific arrays. Specifically, the Human and Mouse, Deluxe Promoter Arrays allow researchers to interrogate all known and alternative start site promoters at ~10kb promoter coverage, all annotated CpG islands (~28,000 for human), and ~500 miRNA promoters on a single glass slide. We have evaluated the reproducibility and quality of the Human Deluxe Promoter arrays immunoprecipitating trimethylation of the histone marks K9 and K27. Our results suggest that NimbleGen ChIP-chip HD2 arrays provide an excellent data correlation within and between HD2 arrays as well as concordance with the well established 385K product line. |
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Roche NimbleGen Webinar Series 
| Date |
Topic |
Speaker |
Download Audio Podcast |
Download Video Podcast |
View Flash Movie |
| Nov 6, 2008 |
Introducing NimbleGen HD2 Arrays for High-Resolution ChIP-chip Analysis |
Dr. leo Iniguez,
Roche NimbleGen |
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| Apr 3, 2008 |
Sequence Capture Technology: Using Microarrays to Capture Megabases of Sequence or Hundreds of Thousands of Human Exons for Next Generation Sequencing |
Dr. Tom Albert,
Roche NimbleGen |
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| Mar 19, 2008 |
Genomic Analyses of Gene Regulation by Poly(ADP-Ribose) Polymerase-1 and Histone H1 |
Dr. Matt Gamble,
Cornell University |
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| Feb 28, 2008 |
Integrated Epigenomic Analyses of Neuronal MeCP2 Reveal a Role for Long-Range Interaction with Active Genes |
Dr. Janine LaSalle,
UC Davis |
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| Nov 29, 2007 |
Genome Architecture and Genomic Disease: A Targeted Approach to Disease Discovery |
Dr. Heather Mefford
University of Washington |
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| Nov 1, 2007 |
Demonstration of KAP1 Binding to Silenced Chromatin with Genome-wide ChIP-chip Analysis |
Dr. Henriette O'Geen
University of California, Davis |
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| Sep 19, 2007 |
Gene Silencing by Large, Non-coding RNAs: The Regulatory Role of HOTAIR analyzed with ChIP-chip and Tiling Expression Analysis |
Dr. John Rinn, Harvard Medical School |
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| Aug 15, 2007 |
Assaying Gene Expression Using NimbleGen Multiplex Arrays: Taking Advantage of High-Throughput Sample Analysis |
Dr. John Manak, Roche NimbleGen |
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| Jul 18, 2007 |
Genome-Wide Distribution, Sequence Determinant and Evolution of CTCF Binding |
Dr. Tae Hoon Kim, Yale University School of Medicine |
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| May 17, 2007 |
MIRA-Assisted Microarrays for DNA Methylation Analysis and Cancer Diagnosis |
Dr. Gerd Pfeifer, Beckman Research Institute, City of Hope |
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| May 8, 2007 |
Microarray-Mediated, Whole-Genome Comparison of the Distribution of RNA Polymerase with the Transcript Map in Escherichia coli |
Dr. Joseph Wade, Harvard University |
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| Apr 11, 2007 |
Part I: A novel genomic disorder affecting neurobehavioral development; fine mapping of rearrangements involving complex low copy repeats on chromosome 10q |
Dr. Scott Selleck, The University of Minnesota |
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| Apr 11, 2007 |
Part II: Using Drosophila to model disruptions of PTEN-TSC-TOR signaling on synapse assembly and behavior |
Dr. Scott Selleck, The University of Minnesota |
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| Mar 13, 2007 |
Efficient High-Resolution Deletion Discovery in Caenorhabditis elegans by Array CGH |
Dr. Jason Maydan, UBC, Vancouver, BC, Canada |
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| Mar 6, 2007 |
Using High-Resolution ChIP-chip to Model Chromatin Signatures of Promoters and Enhancers in the Human Genome |
Dr. Nathaniel Henitzman, LICR, UCSD |
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| Feb 15, 2007 |
High-Resolution Mapping of Copy-Number Variants Genome-Wide with Array CGH |
Timothy A. Graubert, M.D. Washington University, St. Louis |
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| Jan 24, 2007 |
Genome-Wide DNA Methylation Analysis with Immunoprecipitation and Tiling DNA Microarrays |
Dr. Daniel Zilberman, Fred Hutchinson Cancer Research Center |
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| Aug 31, 2006 |
The Discovery and Characterization of Genomic Disorders with High-Resolution Array CGH |
Dr. Andrew Sharp, The University of Washington |
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| Aug 8, 2006 |
AHigh-Resolution Method to Identify DNase I Hypersensitive Sites Using Tiled Microarrays |
Dr. Greg Crawford, Duke University |
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| May 16, 2006 |
Genome-Wide Mapping of Transcriptional Regulatory Elements in Mammalian Cells |
Dr. Bing Ren, UCSD |
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| Feb 6, 2006 |
Identifying Antibiotic Resistance and Other Adaptive Mutations in Helicobacter pylori using NimbleGen CGS Technology |
Dr. Douglas Berg, Washington University |
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Roche NimbleGen Workshops
| Date |
Venue |
Topic |
Speaker |
Download Audio Podcast |
Download Video Podcast |
View Flash Movie |
| Jun 2, 2007 |
ESHG 2008 |
High-Throughput Detection of Exonic Copy-Number Changes Using NimbleGen Oligonucleotide-Based CGH Array Technology |
Dr. Jamel Chelly
Institute Cochin - Hospital Cochin |
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| High-Throughput Approaches for DNA Methylation Profiling |
Dr. Stephan Beck
University College London |
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| Sequence Capture for Medical Sequencing |
Dr. Daniel Turner
Wellcome Trust Sanger Institute |
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| Jan 15, 2008 |
PAG 2008 |
Genome-Scale Targeted Sequencing and Expression Analysis in Duplicated Genomes |
Full Program |
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Direct Genomic Selection by Microarray Hybridization for
High-Throughput Sequencing |
Dr. Xinmin Zhang,
Roche NimbleGen |
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| Insights into the Evolutionary Significance of Whole Genome Duplications Provided by Populus Expression Arrays |
Dr. Steve DiFazio,
West Virginia University |
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| Duplicate gene expression evolution in cotton |
Lex Flagel,
PhD Student
Iowa State University |
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| Oct 25, 2007 |
ASHG 2007 |
NimbleGen Genetics & Epigenetics Workshop, Full Program |
Full Program |
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| Genome-wide scan of copy number variation in autism |
Dr. Jonathan Sebat
Cold Spring Harbor Laboratory |
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| Epigenetic Regulation of the HOX Locus by Non-coding RNAs |
Dr. John Rinn, Harvard Medical School |
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| Application of CGH arrays in DNA Diagnostics |
Dr.Madhuri Hegde
Emory University School of Medicine |
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| Jun 18, 2007 |
ESHG 2007 |
Human Genetics and Epigenetics:
High-Resolution Discovery with Array CGH, DNA Methylation, and ChIP-chip |
Full Program |
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| Towards a comprehensive map of copy number variation in the human genome |
Dr. Matthew Hurles
The Wellcome Trust Sanger Institute, Cambridge |
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Mapping promoter DNA
methylation in mammalian
genomes using oligonucleotide
arrays |
Dr. Michaël Weber
Friedrich Miescher Institute for Biomedical Research, Basel |
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| Combinatorial Effects of Four Histone Modifications in Transcription and Differentiation |
Dr. Silke Sperling
Max Planck Institute for Molecular Genetics, Berlin |
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| Mar 24, 2007 |
ACMG 2007 |
Detection of Microdeletion and Microduplication Disorders Using Ultra-High Resolution array CGH |
Dr. Blake Ballif, Signature Genomic Labs, LLC |
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| Oct 10, 2006 |
ASHG 2006 |
Human Genetics and Epigenetics: High-Resolution Discovery with Array CGH, DNA Methylation, and ChIP-chip |
Full Program |
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| The Discovery and Characterization of Genomic Disorders with High-Resolution Array CGH |
Dr. Andrew Sharp, The University of Washington |
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| Cytosine Methylation Dynamics in Development and Disease |
Dr. John Greally, Albert Einstein College of Medicine |
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| ChIP-Chip'ing Away at the Functions of Proteins Mutated in Genetic Syndromes |
Dr. Peter C. Scacheri, Case Western Reserve University |
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