Human Genome Research
Sequence Capture
NimbleGen Sequence Capture arrays enable you to produce targeted, sequencing-ready samples in your lab for use with next-generation sequencing instruments. Use our array-based Sequence Capture Arrays or the solution-based SeqCap EZ Library product line to accelerate your research project.
CGH/CNV
NimbleGen CNV Arrays are optimized for high-resolution CNV discovery and association studies. CGX Cytogenetics Arrays support genome-wide analysis of DNA copy number changes with a subset of probes focused in disease-associated regions.
- More Human CGH/CNV Arrays...
- Whole-Genome Tiling Arrays
- Cytogenetics Arrays
- CNV Arrays
- Exon-Focused Arrays
- Chromosome Specific Arrays
- Custom Arrays
ChIP-chip
Map target protein DNA binding sites across the entire human genome or within biologically important regions such as promoters. We offer a variety of Human Promoter Arrays in addition to 4 array and 10 array set Human Whole-Genome Tiling Arrays.
- More Human ChIP-chip Arrays...
- Whole-Genome Tiling Arrays
- Promoter Arrays
- Targeted Arrays
- Custom Arrays
DNA Methylation
Identify changes in DNA methylation within promoters, CpG islands, and genic/intergenic regions. Roche NimbleGen CpG Island Plus Promoter, Deluxe Promoter, and Whole-Genome Tiling Sets offer tremendous flexibility for human genome studies.
- More Human DNA Methylation Arrays...
- Whole-Genome Tiling Arrays
- Promoter Arrays
- Targeted Arrays
- Custom Arrays
Gene Expression
Tile through the human genome at any desired spacing to discover genome-wide expression activity in both coding and noncoding regions, and map transcripts with unparalleled accuracy. For maximum flexibility and convenience we offer Human Gene Expression Arrays in three formats: 12x135K, 385K, and 4x72K.
Learn | Literature
- NimbleGen Array Capture Outperforms Two Target-Enrichment Methods in ABRF Research Group Comparison
Reprint - GenomeWeb InSequence (PDF Format 107KB) - NimbleGen Human CGH Whole-Genome Arrays
Brochure (PDF Format 2.2MB) - Human Genome HG18 Annotation Files
Annotation Files (ZIP Format 11.2MB)
What files are included in this download? - NimbleGen ChIP-chip 2.1M Whole-Genome Tiling and Deluxe Promoter Array Delivery
Datasheet (PDF Format 419KB) - Frequent switching of Polycomb repressive marks and DNA hypermethylation in the PC3 prostate cancer cell line
Application Note (PDF Format 914KB)
Learn | Webinars
Casey Matthews
Targeted Re-Sequencing Made Easy: A Core Laboratory’s Experience with NimbleGen SeqCap EZ
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View Flash MovieDr. Andrew Sharp
Methylation Profiling in Uniparental Tissues Identifies Novel Imprinted Genes
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View Flash MovieDr. Scott Selleck
Copy Number Variation in Low Copy Repeat-Rich Regions of the Genome: How Much is There and What Does it Take to Measure It?
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View Flash Movie
Learn | Publications
- Sep 2010 | Hum Mol Genet
Large inverted repeats within Xp11.2 are present at the breakpoints of isodicentric X chromosomes in Turner syndrome. - May 2010 | Nat Genet
Mutation spectrum revealed by breakpoint sequencing of human germline CNVs. - Mar 2010 | Am J Hum Genet
Targeted capture and next-generation sequencing identifies C9orf75, encoding taperin, as the mutated gene in nonsyndromic deafness DFNB79. - Nov 2009 | Leuk Res
Epigenetics of multiple myeloma after treatment with cytostatics and gamma radiation.
